A novel therapeutic giving cancer patients new hope.
We are focused on rapidly advancing our lead therapeutic candidate, misetionamide (GP-2250), for the treatment of multiple cancer types, including ovarian and pancreatic cancers.

OUR SCIENCE
Disrupting cancer cell
metabolism.
Our unique and novel mechanism of action selectively disrupts the energy metabolism of cancer cells
leading to cancer cell death as well as impacting nuclear factor-κB (“NFκB”) which effects cancer cells’
ability for protein synthesis and DNA transcription thereby restricting cancer cell
growth and proliferation.
OUR PIPELINE
Focused on Addressing Unmet Needs For Patients with Cancer.

OVARIAN
CANCER

PANCREATIC
CANCER

ADDITIONAL
TARGETS
Melanoma, Squamous
Cell, Breast, Colorectal
Truly novel.
Truly important.
We are on a mission to improve therapeutic outcomes for cancer patients with misetionamide, a tumor-cell selective agent with a truly novel mechanism of action.

Focused on what
matters most.
In addition to demonstrating direct anti-cancer activity, misetionamide has shown pro-inflammatory cytokine suppression in preclinical studies.
Misetionamide’s inhibition of c-MYC potentially offers the opportunity of enhancing immunotherapy as well.
We have chosen to focus on the treatment of ovarian and pancreatic cancers as our initial indications, two conditions with a clear unmet medical need. Early clinical experience is promising.

The Latest
PUBLICATION
Publication Summary – Misetionamide (GP-2250)
A summary of all publications with links to full document
POSTER
Publication Summary – Misetionamide (GP-2250)
Interim Open-Label Phase 1 Results of Misetionamide (GP-2250): A Small Molecule Antineoplastic That Inhibits Three Major Transcription Factors
PRESS RELEASE - 13 JUNE 2025
Publication Summary – Misetionamide (GP-2250)
A summary of all publications with links to full document
PRESS RELEASE - 14 NOVEMBER 2024
Publication Summary – Misetionamide (GP-2250)
Interim Open-Label Phase 1 Results of Misetionamide (GP-2250): A Small Molecule Antineoplastic That Inhibits Three Major Transcription Factors

+1.610.922.1910
Copyright © 2025 Panavance Therapeutics Inc.
Our Home
About
Resources
Participate